Tag Archives: adverse event

The Futile Quest of Proofing a Negative in the Presence of Overwhelming Absence of Harm

Posted on by — No Comments ↓

The cartilage damage caused by fluoroquinolones in juvenile beagle dogs is not subtle:  blister formation and erosions occur in a dose-dependent fashion resulting in reversible cartilage damage.  These lesions can be seen not just histologically but even macroscopically.  The animals Continue reading The Futile Quest of Proofing a Negative in the Presence of Overwhelming Absence of Harm→

Antibiotics with Ocular Toxicity

Posted on by — 1 Comment ↓

The recent discussion whether fluoroquinolones (FQ) cause retinal detachment was short-lived and soon put to rest.   The issue was raised by 2 observational studies but no signal was seen in a larger and better designed  Danish study.  So it seems Continue reading Antibiotics with Ocular Toxicity→