The Rapid Rise of Sulfonamide Diversity

Shortly after Domagk and Hörlein announced their discovery of the antibacterial properties of the dye sulfamidochrysoidine (Prontosil) in 1935, numerous chemical companies set out to modify the chemical structure.  They soon recognized the sulfa component as the true antibacterial and produced an incredible Continue reading The Rapid Rise of Sulfonamide Diversity