CMV Connections: Paul-Bunnell Negative Mononucleosis and ‘Changelings’

Mononuclesosis is an EBV infection that can be diagnosed with the heterophil antibody test developed by Paul and Bunnell. The test is based on the agglutination of sheep erythrocytes with the blood of EBV infected patients. P-B heterophil serology is negative in ‘mononucleosis’ caused by CMV. In this day and Continue reading CMV Connections: Paul-Bunnell Negative Mononucleosis and ‘Changelings’

Google Search for News on “Antibiotics”

The top-line news articles that come up on a Google search when one enters the term “antibiotics” is truly an eclectic bunch. Here is Page 1 of search results after eliminating some duplications. We have a few comments on these headlines for “Breaking News”. Antibiotics, not surgery, could treat appendicitis Continue reading Google Search for News on “Antibiotics”

All Smiles at the Press Conference: Plazo+Levo Delivers

This December, Achaogen released much data on 2 plazomicin trials[1]: the pivotal EPIC study comparing plazomicin / levofloxacin with meropenem / levofloxacin in cUTI is the one we want to look at today because it is interpretable, while the other trial called CARE is not. CARE is one of those observational Continue reading All Smiles at the Press Conference: Plazo+Levo Delivers