1.0Allphase Pharma Consulting, LLChttps://allphasepharma.com/dirHaraldhttps://allphasepharma.com/dir/author/haraldeva/rich600338<blockquote class="wp-embedded-content" data-secret="QR1zWrKchf"><a href="https://allphasepharma.com/dir/2017/01/09/2993/aradigm-lost-orbit-hayward-problem/">Aradigm Lost in ORBIT – Hayward, We Have a Problem</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://allphasepharma.com/dir/2017/01/09/2993/aradigm-lost-orbit-hayward-problem/embed/#?secret=QR1zWrKchf" width="600" height="338" title="“Aradigm Lost in ORBIT – Hayward, We Have a Problem” — Allphase Pharma Consulting, LLC" data-secret="QR1zWrKchf" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script> /*! This file is auto-generated */ !function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document); //# sourceURL=https://allphasepharma.com/dir/wp-includes/js/wp-embed.min.js </script> https://i0.wp.com/allphasepharma.com/dir/wp-content/uploads/2017/01/Aradigm-slider.jpg?fit=640%2C180&ssl=1640180It is interesting to see how often a discussion of study results moves from microbiology to clinical significance to statistical analysis details. When an antibiotic is not evaluated on the basis of its antimicrobial activity but on its ability to change a clinically relevant measure (the “feel, function, survive” mantra Continue reading →