{"id":521,"date":"2014-07-06T14:42:36","date_gmt":"2014-07-06T14:42:36","guid":{"rendered":"http:\/\/allphasepharma.com\/dir\/?p=521"},"modified":"2014-08-31T16:17:21","modified_gmt":"2014-08-31T20:17:21","slug":"aeromonas-salmonicida-trouble-for-aquaculture-with-drug-resistance","status":"publish","type":"post","link":"https:\/\/allphasepharma.com\/dir\/2014\/07\/06\/521\/aeromonas-salmonicida-trouble-for-aquaculture-with-drug-resistance\/","title":{"rendered":"Aeromonas salmonicida: Trouble for Aquaculture with Drug Resistance"},"content":{"rendered":"

\"Salmon\"<\/a>Aeromonas salmonicida causes furunculosis in salmon hatcheries and in freshwater fish.\u00a0 The organism has several recognized virulence mechanisms including the T3SS\u00a0[1].\u00a0<\/p>\n

A. salmonicida\u00a0has become resistant to penicillin, tetracycline and erythromycin.\u00a0 It remains susceptible to chloramphenicol and aminoglycoside according to a publication from Romania [2] but another reference describes it as resistant to chloramphenicol and sulfonamides as well [3].\u00a0 The frequent use of quinolones undoubtedly contributed to the rapid development of resistance to this drug class[4].\u00a0 An attenuated live vaccine is available and widely used with good effect.<\/p>\n

While considered non-pathogenic to humans, a recent case report from India describes a patient with positive blood cultures for A. salmonicida.\u00a0 The organism was sensitive to multiple antibiotics.\u00a0 Unfortunately, no history regarding exposure to fish is provided; the patient presented with a non-descript febrile illness which responded promptly to cefixime.[5]\u00a0 Possible misidentification of A. salmonicida by automated bacterial identification systems (Vitek) make this case somewhat questionable.<\/p>\n

By contrast, Vibrio salmonicida causes a septic disease.<\/p>\n

\n

 <\/p>\n

References:<\/strong><\/p>\n

[1] Vanden Bergh.\u00a0 http:\/\/www.proteomesci.com\/content\/11\/1\/42<\/a><\/p>\n

[2] http:\/\/www.univagro-iasi.ro\/revista_zoo\/ro\/documente\/Pdf_Vol_57\/Angelica_Docan.pdf<\/a><\/p>\n

[3] http:\/\/microbewiki.kenyon.edu\/index.php\/Aeromonas_salmonicida<\/p>\n

[4] Giraud. J Med Microbiol\u00a02004;. 58:\u00a0895<\/p>\n

[5] Tewari. http:\/\/www.jcdr.net\/articles\/PDF\/4032\/43-%206883_F(P)_PF1(PAK)_PFA(AK)_NEW.pdf<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Aeromonas salmonicida causes furunculosis in salmon hatcheries and in freshwater fish.\u00a0 The organism has several recognized virulence mechanisms including the T3SS\u00a0[1].\u00a0<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[140],"tags":[255,176,403,266,256,265,264,221,261,162,259,182,262,141,205,263,257,258,260],"class_list":["post-521","post","type-post","status-publish","format-standard","hentry","category-interesting_facts","tag-aeromonas-salmonicida","tag-aminoglycoside","tag-antibiotic-blog","tag-antibiotic-resistance","tag-aquaculture","tag-cefixime","tag-chloramphenicol","tag-erythromycin","tag-furunculosis","tag-penicillin","tag-quinolone-resistance","tag-resistance","tag-sepsis","tag-sulfonamide","tag-t3ss","tag-tetracycline","tag-vaccine","tag-vibrio-salmonicida","tag-vitek"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_shortlink":"https:\/\/wp.me\/p4KWFr-8p","jetpack_sharing_enabled":true,"jetpack-related-posts":[{"id":1178,"url":"https:\/\/allphasepharma.com\/dir\/2014\/12\/19\/1178\/nominating-thiamphenicol-for-idsas-10-x-20-campaign\/","url_meta":{"origin":521,"position":0},"title":"Nominating Thiamphenicol for IDSA\u2019s 10 x \u201920 Campaign","author":"Harald","date":"December 19, 2014","format":false,"excerpt":"If you were developing a new antibiotic with a novel MoA, one that covers most GPC, most GNR, most anaerobes and atypicals, including many MDR pathogens like MRSA, enterococci (both E. faecalis and E. faecium), and one that has also activity against\u00a0rickettsiae and bioterrorism agents, you would consider it a\u2026","rel":"","context":"In "QIDP Antibiotics"","block_context":{"text":"QIDP Antibiotics","link":"https:\/\/allphasepharma.com\/dir\/category\/qidp_antibiotic\/"},"img":{"alt_text":"Aplastic Anemia","src":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2014\/12\/Aplastic-Anemia.jpg?resize=350%2C200","width":350,"height":200},"classes":[]},{"id":6294,"url":"https:\/\/allphasepharma.com\/dir\/2026\/03\/14\/6294\/where-are-the-chloramphenicol-derivatives\/","url_meta":{"origin":521,"position":1},"title":"Where are the Chloramphenicol Derivatives?","author":"Harald","date":"March 14, 2026","format":false,"excerpt":"The 1st edition of Mandell's textbook 'Principles and Practice of Infectious Disease' was published in 1979.\u00a0 It has grown ever since in size and numbers of chapters.\u00a0 Now in its 10th edition, it is and remains an impressive publication, a 2-volume set, a comprehensive reference textbook, kept up-to-date with periodic\u2026","rel":"","context":"In "Did you know...?"","block_context":{"text":"Did you know...?","link":"https:\/\/allphasepharma.com\/dir\/category\/interesting_facts\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2026\/02\/amphenicols.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2026\/02\/amphenicols.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2026\/02\/amphenicols.jpg?resize=525%2C300&ssl=1 1.5x"},"classes":[]},{"id":1385,"url":"https:\/\/allphasepharma.com\/dir\/2015\/04\/21\/1385\/an-inconvenient-truth-ciprofloxacin-resistant-campylobacter\/","url_meta":{"origin":521,"position":2},"title":"An Inconvenient Truth: Ciprofloxacin-Resistant Campylobacter","author":"Harald","date":"April 21, 2015","format":false,"excerpt":"When Al Gore became a best-selling author with \u201cAn Inconvenient Truth\u201d he warned about climate change.\u00a0 When it comes to antibiotic resistance and the current situation of \u201cBad Bugs, No Drugs\u201d, there are many voices warning us about a return to the pre-antibiotic era. Why does it take so long\u2026","rel":"","context":"In "The Viewpoint"","block_context":{"text":"The Viewpoint","link":"https:\/\/allphasepharma.com\/dir\/category\/the_viewpoint\/"},"img":{"alt_text":"An Inconv T","src":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2015\/04\/An-Inconv-T.jpg?resize=350%2C200","width":350,"height":200},"classes":[]},{"id":1722,"url":"https:\/\/allphasepharma.com\/dir\/2015\/07\/15\/1722\/streptomyces-the-industrious-antibiotic-producer\/","url_meta":{"origin":521,"position":3},"title":"Streptomyces \u2013 The Industrious Antibiotic Producer","author":"Harald","date":"July 15, 2015","format":false,"excerpt":"Like other\u00a0actinomycetes, the Streptomyces group of microbes straddles the somewhat artificial boundary between bacteria and fungi.\u00a0Growth on culture plates looks 'fungal' and the organism produces spores and germtubes that look like mycelia.\u00a0 Nonetheless these soil organisms are bacteria and of great interest to microbiologists as the producers of many antibiotics\u2026","rel":"","context":"In "Did you know...?"","block_context":{"text":"Did you know...?","link":"https:\/\/allphasepharma.com\/dir\/category\/interesting_facts\/"},"img":{"alt_text":"Streptomyces slider-2 copy","src":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2015\/07\/Streptomyces-slider-2-copy.jpg?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2015\/07\/Streptomyces-slider-2-copy.jpg?resize=350%2C200 1x, https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2015\/07\/Streptomyces-slider-2-copy.jpg?resize=525%2C300 1.5x"},"classes":[]},{"id":1254,"url":"https:\/\/allphasepharma.com\/dir\/2015\/02\/02\/1254\/a-go-no-go-decision-delafloxacin-stumbles-in-gonorrhea-study\/","url_meta":{"origin":521,"position":4},"title":"A GO \/ NO GO decision:\u00a0 Delafloxacin Stumbles in Gonorrhea Study","author":"Harald","date":"February 2, 2015","format":false,"excerpt":"The treatment history of N. gonorrhoeae makes for fascinating reading.\u00a0 This organism has always been able to keep the upper hand in the war of bug versus drug.\u00a0 Once susceptible to sulfa drugs, to penicillin, tetracyclines and fluoroquinolones, it sequentially become resistant in the matter of a decade to every\u2026","rel":"","context":"In "Did you know...?"","block_context":{"text":"Did you know...?","link":"https:\/\/allphasepharma.com\/dir\/category\/interesting_facts\/"},"img":{"alt_text":"mic-2","src":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2015\/02\/mic-2.jpg?resize=350%2C200","width":350,"height":200},"classes":[]},{"id":1488,"url":"https:\/\/allphasepharma.com\/dir\/2015\/05\/26\/1488\/treating-gc-in-the-face-of-dwindling-antibiotic-options-1\/","url_meta":{"origin":521,"position":5},"title":"Treating GC in the Face of Dwindling Antibiotic Options \u2013 (1)","author":"Harald","date":"May 26, 2015","format":false,"excerpt":"Looking across the Northern border it is clear that CDC Guidelines are not universally followed even in North America. Public Health Canada still recommends cefixime for uncomplicated gonorrhea (GC), albeit at the high single oral dose of 800 mg\u00a0[1]. In the US, CDC has opted for combination treatment with ceftriaxone\u2026","rel":"","context":"In "Did you know...?"","block_context":{"text":"Did you know...?","link":"https:\/\/allphasepharma.com\/dir\/category\/interesting_facts\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2015\/05\/GC-slider1.jpg?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2015\/05\/GC-slider1.jpg?resize=350%2C200 1x, https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2015\/05\/GC-slider1.jpg?resize=525%2C300 1.5x"},"classes":[]}],"jetpack_likes_enabled":true,"_links":{"self":[{"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/posts\/521","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/comments?post=521"}],"version-history":[{"count":6,"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/posts\/521\/revisions"}],"predecessor-version":[{"id":812,"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/posts\/521\/revisions\/812"}],"wp:attachment":[{"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/media?parent=521"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/categories?post=521"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/tags?post=521"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}