{"id":900,"date":"2014-09-21T23:13:14","date_gmt":"2014-09-22T03:13:14","guid":{"rendered":"http:\/\/allphasepharma.com\/dir\/?p=900"},"modified":"2014-09-24T00:36:27","modified_gmt":"2014-09-24T04:36:27","slug":"8th-edition-mandell-principles-and-practice-of-infectious-diseases","status":"publish","type":"post","link":"https:\/\/allphasepharma.com\/dir\/2014\/09\/21\/900\/8th-edition-mandell-principles-and-practice-of-infectious-diseases\/","title":{"rendered":"Fantastic &#8211; The 8th Edition of Mandell&#8217;s is Here!"},"content":{"rendered":"<p>It has grown with each edition, in page numbers, in weight, in numbers of contributors, diseases and pathogens described, and in complexity, with online access and search capabilities.<\/p>\n<p>More than most other therapeutic areas, the science of ID has grown in the past decades, thanks to advances in genetics, diagnostics and immunology.\u00a0 The discovery of so many new pathogens in recent years has made the field challenging and exciting, requiring constant updates in knowledge and revision of prior assumptions.<!--more--><\/p>\n<p>So, after only a 4-year hiatus, the \u2018new Mandell\u2019 was released on Sept 11, 2014.<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2014\/09\/Mandell-e8.jpg?ssl=1\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-903\" src=\"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2014\/09\/Mandell-e8.jpg?resize=246%2C318&#038;ssl=1\" alt=\"PPID 8th Edition\" width=\"246\" height=\"318\" \/><\/a>I assume it will take a good long time for even the most dedicated reviewer to thoroughly check its 324 chapters.\u00a0 Once done, the verdict will certainly be as ecstatic in the past: \u00a0an indispensable tome for the ID specialist, a \u2018must-have\u2019 for medical libraries, to be used as the ultimate reference text for all things infectious diseases.<\/p>\n<p>We should all be grateful to the authors and publishing team for all their work and dedication to the project.\u00a0 Putting it all together must have been a truly Herculean effort.<\/p>\n<p>While we want to give praise where it is due, a few thoughts\u00a0can be shared\u00a0already now.<\/p>\n<p>First, one wonders whether the book format is still justified in this age of rapid-fire changes in knowledge.\u00a0 In the electronic world we live in, a regularly updated cloud-based \u201cliving document\u2019 may be easier to maintain and keep fresh.\u00a0 For instance, the stream of new data in the HCV area is impossible to capture in a printed book which sees revisions only every 4-5 years.\u00a0 The publisher (Elsevier) has recognized this shortcoming already some time ago and will probably add electronic updates to the on-line version on a regular basis, however, the hard-cover book is what it is.<\/p>\n<p>A second more provocative thought is about the roster of authors.\u00a0 Quite frankly, this selection\u00a0seems a bit \u2018cliquish\u2019: so many \u201cdoyens\u201d of infectious diseases who were involved in the last 5 editions (or more) are still writing their favorite chapters and are only slowly relinquishing control to some hand-picked disciples.\u00a0 This comes at the expense of fresh approaches and significant re-writes.<\/p>\n<p>Third point:\u00a0 The authorship is almost exclusively from the US.\u00a0 Why not engage a more international group of contributors?\u00a0 There are some notable exceptions, of course, mainly from the English-speaking world.\u00a0 Nonetheless, as it stands, this book reflects largely \u201cUS principles and practice\u201d.\u00a0 Maybe one of the next editions could take a more multi-national and pluralistic\u00a0approach to authorship.<\/p>\n<p>If you are looking for an authoritative textbook, written by the \u201cWho is who\u201d in infectious diseases, this incarnation of Mandell\u2019s will not disappoint.<\/p>\n<p>I will review some of the chapters on this blog and report my impressions.\u00a0 In the meantime: A bientot !\u00a0 Arrivederci !\u00a0 Hasta la vista !\u00a0 Namaste !\u00a0 Maa salama !<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>It has grown with each edition, in page numbers, in weight, in numbers of contributors, diseases and pathogens described, and in complexity, with online access and search capabilities. More than most other therapeutic areas, the science of ID has grown in the past decades, thanks to advances in genetics, diagnostics <a class=\"more-link\" href=\"https:\/\/allphasepharma.com\/dir\/2014\/09\/21\/900\/8th-edition-mandell-principles-and-practice-of-infectious-diseases\/\">Continue reading <span class=\"screen-reader-text\">  Fantastic &#8211; The 8th Edition of Mandell&#8217;s is Here!<\/span><span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":904,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[227,3,18],"tags":[403,542,543],"class_list":["post-900","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-recent_literature","category-the_news","category-the_viewpoint","tag-antibiotic-blog","tag-mandell-principles-and-practice-of-infectious-diseases","tag-mandells"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2014\/09\/Mandell-x-4.jpg?fit=640%2C200&ssl=1","jetpack_shortlink":"https:\/\/wp.me\/p4KWFr-ew","jetpack_sharing_enabled":true,"jetpack-related-posts":[{"id":1092,"url":"https:\/\/allphasepharma.com\/dir\/2014\/10\/31\/1092\/ebola-transmission-prevention\/","url_meta":{"origin":900,"position":0},"title":"Preventing Ebola Transmission","author":"Harald","date":"October 31, 2014","format":false,"excerpt":"Chapter 166\u00a0[1] in the new Mandell textbook was written before the current Ebola outbreak, so I thought it would be interesting to read View Postit again and check whether the \u2018old\u2019 recommendations for personal protection were still valid now that we have learned much more during the ongoing outbreak. In\u2026","rel":"","context":"In &quot;The Viewpoint&quot;","block_context":{"text":"The Viewpoint","link":"https:\/\/allphasepharma.com\/dir\/category\/the_viewpoint\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2014\/10\/Lego-Hazmat-copy.jpg?fit=640%2C200&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2014\/10\/Lego-Hazmat-copy.jpg?fit=640%2C200&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2014\/10\/Lego-Hazmat-copy.jpg?fit=640%2C200&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":1401,"url":"https:\/\/allphasepharma.com\/dir\/2015\/04\/30\/1401\/a-renaissance-for-old-drugs-fosfomycin-and-colistin\/","url_meta":{"origin":900,"position":1},"title":"A Renaissance for Old Drugs: Fosfomycin and Colistin","author":"Harald","date":"April 30, 2015","format":false,"excerpt":"Fosfomycin Who would have thought that a drug that has been around since 1969 [2] could become eligible for QIDP status in 2015? Well, Zavante Therapeutics recently garnered the coveted QIDP designation for fosfomycin IV. This formulation has been available in Europe for a quite some\u00a0time but not in the\u2026","rel":"","context":"In &quot;QIDP Antibiotics&quot;","block_context":{"text":"QIDP Antibiotics","link":"https:\/\/allphasepharma.com\/dir\/category\/qidp_antibiotic\/"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":5219,"url":"https:\/\/allphasepharma.com\/dir\/2025\/09\/03\/5219\/listeria-food-recalls-outbreaks-and-resistance\/","url_meta":{"origin":900,"position":2},"title":"LISTERIA: Food Recalls, Outbreaks, and Resistance","author":"Harald","date":"September 3, 2025","format":false,"excerpt":"You may be aware of recent food product recalls associated with food poisoning due to listeria contamination: ready-to-eat products, deli meats, sandwiches, protein snacks, chicken, turkey, cheese and dairy products.\u00a0 The list is long as Listeria is ubiquitous in the environment.\u00a0 One can find it in meat and milk\/cheese products\u2026","rel":"","context":"In &quot;Did you know...?&quot;","block_context":{"text":"Did you know...?","link":"https:\/\/allphasepharma.com\/dir\/category\/interesting_facts\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2025\/09\/image-1.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2025\/09\/image-1.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2025\/09\/image-1.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2025\/09\/image-1.png?resize=700%2C400&ssl=1 2x"},"classes":[]},{"id":6294,"url":"https:\/\/allphasepharma.com\/dir\/2026\/03\/14\/6294\/where-are-the-chloramphenicol-derivatives\/","url_meta":{"origin":900,"position":3},"title":"Where are the Chloramphenicol Derivatives?","author":"Harald","date":"March 14, 2026","format":false,"excerpt":"The 1st edition of Mandell's textbook 'Principles and Practice of Infectious Disease' was published in 1979.\u00a0 It has grown ever since in size and numbers of chapters.\u00a0 Now in its 10th edition, it is and remains an impressive publication, a 2-volume set, a comprehensive reference textbook, kept up-to-date with periodic\u2026","rel":"","context":"In &quot;Did you know...?&quot;","block_context":{"text":"Did you know...?","link":"https:\/\/allphasepharma.com\/dir\/category\/interesting_facts\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2026\/02\/amphenicols.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2026\/02\/amphenicols.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2026\/02\/amphenicols.jpg?resize=525%2C300&ssl=1 1.5x"},"classes":[]},{"id":1178,"url":"https:\/\/allphasepharma.com\/dir\/2014\/12\/19\/1178\/nominating-thiamphenicol-for-idsas-10-x-20-campaign\/","url_meta":{"origin":900,"position":4},"title":"Nominating Thiamphenicol for IDSA\u2019s 10 x \u201920 Campaign","author":"Harald","date":"December 19, 2014","format":false,"excerpt":"If you were developing a new antibiotic with a novel MoA, one that covers most GPC, most GNR, most anaerobes and atypicals, including many MDR pathogens like MRSA, enterococci (both E. faecalis and E. faecium), and one that has also activity against\u00a0rickettsiae and bioterrorism agents, you would consider it a\u2026","rel":"","context":"In &quot;QIDP Antibiotics&quot;","block_context":{"text":"QIDP Antibiotics","link":"https:\/\/allphasepharma.com\/dir\/category\/qidp_antibiotic\/"},"img":{"alt_text":"Aplastic Anemia","src":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2014\/12\/Aplastic-Anemia.jpg?resize=350%2C200","width":350,"height":200},"classes":[]},{"id":2186,"url":"https:\/\/allphasepharma.com\/dir\/2015\/12\/19\/2186\/aztreonam-plus-avibactam-a-new-bright-star-in-the-night-sky\/","url_meta":{"origin":900,"position":5},"title":"Aztreonam PLUS Avibactam \u2013 A New Bright Star in the Night Sky","author":"Harald","date":"December 19, 2015","format":false,"excerpt":"Looking at the molecular structure of ceftazidime (CTAZ) and aztreonam (ATM), the differences are clear, and so are the similarities: ATM does not have the cephem ring structure of CTAZ, only the 4-member beta-lactam ring.\u00a0 However, the side chains are identical in both CTAZ and ATM which explains the overlapping\u2026","rel":"","context":"In &quot;Recent Literature&quot;","block_context":{"text":"Recent Literature","link":"https:\/\/allphasepharma.com\/dir\/category\/recent_literature\/"},"img":{"alt_text":"Avibactam - slider","src":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2015\/12\/Avibactam-slider.jpg?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2015\/12\/Avibactam-slider.jpg?resize=350%2C200 1x, https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2015\/12\/Avibactam-slider.jpg?resize=525%2C300 1.5x, https:\/\/i0.wp.com\/allphasepharma.com\/dir\/wp-content\/uploads\/2015\/12\/Avibactam-slider.jpg?resize=700%2C400 2x"},"classes":[]}],"jetpack_likes_enabled":true,"_links":{"self":[{"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/posts\/900","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/comments?post=900"}],"version-history":[{"count":7,"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/posts\/900\/revisions"}],"predecessor-version":[{"id":912,"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/posts\/900\/revisions\/912"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/media\/904"}],"wp:attachment":[{"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/media?parent=900"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/categories?post=900"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/allphasepharma.com\/dir\/wp-json\/wp\/v2\/tags?post=900"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}