COMPARISON OF BAFF / APRIL INHIBITORS

First, a reminder where the name ‘Berger’s disease’ or Morbus Berger comes from. It was Jean Berger, a French pathologist and doctor, who initially identified IgA deposits on the glomeruli of nephritic patients.  This was not so long ago; his publication (in French) dates from 1968.[1] Now the race is heating Continue reading COMPARISON OF BAFF / APRIL INHIBITORS

TELITACICEPT IN SLE

In today’s blog we will share our thoughts about a recent NEJM article, entitled “A Phase 3 Trial of Telitacicept for Systemic Lupus Erythematosus”.[1] Publications on SLE literally come with a book of abbreviations and definitions nowadays and are not an easy Sunday reads.  Of course, there is extensive literature Continue reading TELITACICEPT IN SLE

The Antifungal Landscape – 2

As many in the field have said before, what we really need are antifungals with a truly novel MoA, not minor changes to well-established classes.[1]  There is a shortage of new antifungals for invasive disease. Small improvements in PK will hardly move the field forward or excite investors to engage. Our current Continue reading The Antifungal Landscape – 2