Allphase Pharma Consulting, LLC
A Professional Service Provider for the Pharma Industry
This is a somewhat nostalgic retro blog. I was leafing through a book by Vince Andriole called ‘The Quinolones’.[1] First released in 1988, its third edition is from 2000. It provided in-depth coverage of quinolone chemistry, PK, microbiology, efficacy and safety. It was a great review of the large and Continue reading ANTIBIOTIC DEVELOPMENT IN PHARMA IS DEAD – FOR NOW
Just imagine you were tasked to conduct a seasonal flu study in household contacts of a symptomatic index case. Your intervention may be (your choice): pre-season vaccination, pre-exposure prophylaxis, or some non-anti-infective protective measure such as wearing a face mask, taking a vitamin or analgesic that is believed to confer Continue reading Ensitrelvir for Covid Prevention: This Emperor Has No Clothes
Quick: What do you associate with the abbreviation ‘TCR’? Does your immunology-trained mind automatically default to ‘T-cell receptor’? Or is your first guess ‘Tissue Cross Reactivity? Our neural networks can deal with ambivalence and will make the right associations, eventually. Language is imprecise by design and allows for wobble. Things Continue reading OFF-TARGET ANTIBODIES