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Tag Archives: bone penetration

Adequate Penetration of Daptomycin Into Bone Tissue

Posted on July 2, 2014 by Harald — No Comments ↓

After a single high dose of (8 or 10 mg/kg BW) of daptomycin IV, bone levels were measured in plasma and trabecular bone obtained during hip or knee surgery of 16 patients.[1] At the time of surgery, mean concentrations in plasma and synovial fluid were 39 and 22 µg/mL, respectively.  Continue reading Adequate Penetration of Daptomycin Into Bone Tissue→

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Posted in QIDP Antibiotics, Recent Literature, The Viewpoint | Tagged antibiotic blog, bone penetration, Cubicin, Cubist, dalbavancin, Dalvance, daptomycin, endocarditis, Francis Tally, lipoglycopeptide, Orbactiv, oritavancin, osteomyelitis, prosthetic joint infection, QIDP | Leave a reply
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