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Spirochetal colitis or swine dysentery is a disease of piglets with worldwide distribution. It can cause severe bloody diarrheal disease with a mortality of up to 50% in herds if untreated and thus can have great economic impact. The disease has been nearly eradicated in the US but periodically outbreaks Continue reading Pleuromutilins Are Important to Control Brachyspira hyodysenteriae
Several antibiotic classes are associated with QTc prolongation: macrolides, quinolones, the antimalarials that share the quinine structure, and many azole antifungals. FDA warned about the proarrhythmic effects of azithromycin in 2013 [i] but it is a recent publication by Rao which brings the message home again with some very disquieting Continue reading QT Prolongation with Azithromycin and Levofloxacin