The Difficult Transition Into Phase 3

Preclinical and early clinical development is expensive enough already for VC companies but it gets really expensive in Phase 3.  Hence, not surprisingly, few small companies tackle Phase 3 programs on their own.  Unless an ‘angel investor’ with deep pockets commits to the compound and assures continuity of development, the Continue reading The Difficult Transition Into Phase 3

SARS and MERS – a Comparison of the New Corona Viruses

This compilation is from many sources and necessarily incomplete as we still have lots to learn about MERS. Please come back periodically for updated information. Status: 7/8/2014 Some tidbits of unknown significance: A close relative of MERS-CoV is carried by the European hedgehog (Erinaceus europaeus).  As many children have hedgehogs Continue reading SARS and MERS – a Comparison of the New Corona Viruses

Pleuromutilins Are Important to Control Brachyspira hyodysenteriae

Spirochetal colitis or swine dysentery is a disease of piglets with worldwide distribution.  It can cause severe bloody diarrheal disease with a mortality of up to 50% in herds if untreated and thus can have great economic impact.  The disease has been nearly eradicated in the US but periodically outbreaks Continue reading Pleuromutilins Are Important to Control Brachyspira hyodysenteriae