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Tag Archives: biomarker for ALS

VRG50635 – Lessons Learned in ALS

Posted on October 5, 2026 by Harald — No Comments ↓

In a recent blog we took issue with a Nature article about ‘Lessons learned’ after a TIGIT inhibitor failed in late Phase 3 development.  We felt that the article provided few insights, mainly platitudes. This week we saw a different kind of post-mortem.  It was about VRG50635, a PIKfyve inhibitor Continue reading VRG50635 – Lessons Learned in ALS→

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Posted in Recent Literature, The News, The Viewpoint | Tagged Allphase Pharma Consulting, ALS, Amplyx, AMX0035, apilimod, biomarker for ALS, FDA Ad Board, GFAP, Harald Reinhart, lessons learned, NFL, PIKfyve inhibitors, post-mortem for failed drugs, riluzole, TIGIT inhibitor, Verge Genomics, Verge Labs, VRG50635 | Leave a reply

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