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The recent discussion whether fluoroquinolones (FQ) cause retinal detachment was short-lived and soon put to rest. The issue was raised by 2 observational studies but no signal was seen in a larger and better designed Danish study. So it seems the association is probably spurious [i].
Several antibiotic classes are associated with QTc prolongation: macrolides, quinolones, the antimalarials that share the quinine structure, and many azole antifungals. FDA warned about the proarrhythmic effects of azithromycin in 2013 [i] but it is a recent publication by Rao which brings the message home again with some very disquieting Continue reading QT Prolongation with Azithromycin and Levofloxacin