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Tag Archives: IGNITE

Some Thoughts about Eravacycline Based on the Phase 2 cIAI Study

Posted on August 4, 2014 by Harald — No Comments ↓

Solomkin et al. conclude that the efficacy and safety of eravacycline compares favorably to the control drug, ertapenem.[1]  This top-level assessment is made with the usual caveats (insufficient statistical power, small sample size), but a few points deserve comment. Eravacycline is a fluorocycline; as a tetracycline derivative it follows into Continue reading Some Thoughts about Eravacycline Based on the Phase 2 cIAI Study→

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Posted in QIDP Antibiotics, The News | Tagged acinetobacter, antibiotics blog, bioequivalence, CAP, ceftibiprole, cIAI, cSSSI, cUTI, doripenem, dose-finding, doxycycline, eravacycline, ertapenem, ESBL, FDA, GI toxicity, HAP/VAP, IGNITE, omadacycline, Paratek, PK/PD, QIDP, step-down therapy, tetracycline, Tetraphase, tigecycline, Tygacil, Wyeth | Leave a reply

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