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Tag Archives: PK/PD modelling

To Kill A Mocking Bug – of the CRKP or CRAB Variety

Posted on January 24, 2017 by Harald — No Comments ↓

Meropenem stands out as an antibiotic to be used first in ESBL and MDR infections, given its efficacy profile and safety record (see earlier blog). It also would seem to be appropriate to use relatively high doses or prolonged infusion times – or both – to improve T>MIC for the Continue reading To Kill A Mocking Bug – of the CRKP or CRAB Variety→

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Posted in Recent Literature, The News, The Viewpoint | Tagged acinetobacter, Allphase Pharma Consulting, aminoglycoside, antibiotic blog, antibiotic synergy, BL/BLI combination, carbapenem-resistant Klebsiella, colistin, CRAB, CRKP, Doribax, doripenem, Harald Reinhart, imipenem, imipenem side effect, meropenem, Merrem, penems and seizure, PK/PD modelling, polymyxin B, Primaxin, prolonged infusion, renal toxicity, Spero Therapeutics, SPR-741, T>MIC, tigecycline, Tygacil, VABP | Leave a reply

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