Pleuromutilins Are Important to Control Brachyspira hyodysenteriae

Spirochetal colitis or swine dysentery is a disease of piglets with worldwide distribution.  It can cause severe bloody diarrheal disease with a mortality of up to 50% in herds if untreated and thus can have great economic impact.  The disease has been nearly eradicated in the US but periodically outbreaks Continue reading Pleuromutilins Are Important to Control Brachyspira hyodysenteriae

Aeromonas salmonicida: Trouble for Aquaculture with Drug Resistance

Aeromonas salmonicida causes furunculosis in salmon hatcheries and in freshwater fish.  The organism has several recognized virulence mechanisms including the T3SS [1]. 

Strep Infections in High Places

George Washington, age 67,  had a bad peritonsillar or epiglottal abscess; indeed, he died from it as his personal physicians resorted to extensive blood letting and did not dare lance the abscess.  He would have recovered with penicillin, I guess, but in his days the best treatment option for quinsy was surgical drainage. Continue reading Strep Infections in High Places