NANOBODIES FOR AUTOIMMUNE DISEASES

Thrombotic thrombocytopenic purpura (TTP) is a devastating disease with a downhill course of neurologic, renal and cardiac complications leading to death at a young age if untreated.  Thrombocytopenia and thrombosis are its hallmark, with fever, anemia and neurologic deficits. It is caused by large aggregates of vWF, a protein which Continue reading NANOBODIES FOR AUTOIMMUNE DISEASES

About A Prepared Mind – In R&D

“Chance favors the prepared mind” is the short form of a statement by Louis Pasteur which actually reads: “In the fields of observation chance favours only the prepared mind” or ” Dans les champs de l’observation le hasard ne favorise que les esprits prepares”. [1] There is no better example Continue reading About A Prepared Mind – In R&D

The 10 x ’20 Initiative – A Retrospective

It started all so well with fanfare and great expectations. Fifteen years ago, the 10 x ’20 initiative got underway. Its goals were spelled out clearly: To ‘Pursue a Global Commitment to Develop 10 New Antibacterial Drugs by 2020 ’[3].  It was driven by ID clinicians and by antibiotic developers concerned Continue reading The 10 x ’20 Initiative – A Retrospective