The 10 x ’20 Initiative – A Retrospective

It started all so well with fanfare and great expectations. Fifteen years ago, the 10 x ’20 initiative got underway. Its goals were spelled out clearly: To ‘Pursue a Global Commitment to Develop 10 New Antibacterial Drugs by 2020 ’[3].  It Continue reading The 10 x ’20 Initiative – A Retrospective

There is Momentum Building for RSV Therapeutics

Sometimes – for no obvious reason – there is a flurry of publications from a particular area which has been quiet for a long time.  RSV is such an area where new drug development had a hard time getting started.  Continue reading There is Momentum Building for RSV Therapeutics

Learning from Set-Backs: The Frustrating Search for a Staphylococcal Vaccine

Several reasons have been proposed as explanations why so many S. aureus vaccines have failed in clinical trials.  Clearly, the organism has a battery of virulence factors which may require a multipronged approach and neutralizing just a single mechanism with a specific mAb Continue reading Learning from Set-Backs: The Frustrating Search for a Staphylococcal Vaccine