Skip to content

Allphase Pharma Consulting, LLC

A Professional Service Provider for the Pharma Industry

Allphase Pharma Consulting, LLC
Menu

Primary menu

  • CONTACT
  • BLOGS
    • The Viewpoint
    • The News
    • Recent Literature
    • Did you know…?
    • QIDP Antibiotics
  • LEGAL
  • WELCOME

Secondary menu

  • The News
  • The Viewpoint
  • Did you know…?
  • Recent Literature
  • QIDP Antibiotics

Tag Archives: data safety monitoring board

The Futile Quest of Proofing a Negative in the Presence of Overwhelming Absence of Harm

Posted on September 3, 2014 by Harald — No Comments ↓

The cartilage damage caused by fluoroquinolones in juvenile beagle dogs is not subtle:  blister formation and erosions occur in a dose-dependent fashion resulting in reversible cartilage damage.  These lesions can be seen not just histologically but even macroscopically.  The animals are unable to walk as weight-bearing joints are predominantly affected.  Continue reading The Futile Quest of Proofing a Negative in the Presence of Overwhelming Absence of Harm→

Share this:

  • Click to share on LinkedIn (Opens in new window) LinkedIn
  • Click to share on Facebook (Opens in new window) Facebook
  • Click to share on X (Opens in new window) X
  • Click to print (Opens in new window) Print
  • Click to email a link to a friend (Opens in new window) Email
  • Click to share on WhatsApp (Opens in new window) WhatsApp

Like this:

Like Loading...
Posted in Recent Literature, The Viewpoint | Tagged acute otitis media, adverse event, antibiotic blog, AOM, arthropathy, azithromycin, beagle dogs, cartilage damage, Cipro, ciprofloxacin, data safety monitoring board, DSMB, FDA, fluoroquinolones, J&J, juvenile beagles, Levaquin, levofloxacin, musculoskeletal, NoEL, package insert, pediatric use, tramadol, Warnings/Precautions | Leave a reply

Go back

Your message has been sent

Rating(required)
Warning

Footer Menu

Footer menu

  • CONTACT
  • BLOGS
  • LEGAL
  • WELCOME
  • Email
Copyright © 2026 Allphase Pharma Consulting, LLC. All Rights Reserved.
Theme: Catch Box by Catch Themes
Scroll Up
%d