ANTIBIOTIC DEVELOPMENT IN PHARMA IS DEAD – FOR NOW

This is a somewhat nostalgic retro blog.  I was leafing through a book by Vince Andriole called ‘The Quinolones’.[1]  First released in 1988, its third edition is from 2000.  It provided in-depth coverage of quinolone chemistry, PK, microbiology, efficacy and safety.  It was a great review of the large and Continue reading ANTIBIOTIC DEVELOPMENT IN PHARMA IS DEAD – FOR NOW

Where are the Chloramphenicol Derivatives?

The 1st edition of Mandell’s textbook ‘Principles and Practice of Infectious Disease’ was published in 1979.  It has grown ever since in size and numbers of chapters.  Now in its 10th edition, it is and remains an impressive publication, a 2-volume set, a comprehensive reference textbook, kept up-to-date with periodic Continue reading Where are the Chloramphenicol Derivatives?

ANTIBIOTIC USE IN VETERINARY MEDICINE

A ton is a tonne, by any other name.  A tonne, also called a metric tonne, is the equivalent of 1,000 kg.  There are also imperial tonnes and long tonnes which have a slightly different conversion factor:  1 tonne of either is equivalent to 1.01604691 metric tonnes. The amount of Continue reading ANTIBIOTIC USE IN VETERINARY MEDICINE