Dalbavancin Sale to Actavis

When Pfizer bought dalbavancin and anidulofungin from Vicuron in 2005, it shelled out USD 1.9 billion for both Phase 3 drugs.  One can argue whether each drugs had the same commercial value for Pfizer but it is safe to assume that dalbavancin was valued at approx. USD 1 billion at Continue reading Dalbavancin Sale to Actavis

Nikkomycins Are Finally Getting Some Respect

Besides azoles, candins and the polyene class of antifungals there is not much to select from when it comes to systemic fungal infections.  Until the recent arrival of voriconazole and posaconazole, infections caused by molds always required amphotericin B to control.  Only for Candida several good treatments exist on the Continue reading Nikkomycins Are Finally Getting Some Respect

What’s in a Name?  Would ‘Carbavance’ Still Smell as Sweet?

Since the publication of a series of posters at ICAAC 2014, we finally know what’s hidden behind the ‘Carbavance’ name.  ‘Carbavance’ stands for the combination of meropenem with the B-lactamase inhibitor RPX7009 which The Medicines Company (TMC) inlicensed from Rempex Pharmaceuticals a few years ago.  This is the ‘Carbavance’ which Continue reading What’s in a Name?  Would ‘Carbavance’ Still Smell as Sweet?