Allphase Pharma Consulting, LLC
A Professional Service Provider for the Pharma Industry
This compilation is from many sources and necessarily incomplete as we still have lots to learn about MERS. Please come back periodically for updated information. Status: 7/8/2014 Some tidbits of unknown significance: A close relative of MERS-CoV is carried by the European hedgehog (Erinaceus europaeus). As many children have hedgehogs Continue reading SARS and MERS – a Comparison of the New Corona Viruses
At a still earlier stage of development, we found some exciting anti-pseudomonal compounds. First, there is BAL-30072, a sulfactam-derivative. It has an interesting dual MoA as it works not only as a traditional B-lactam but also as an Fe-chelator blocking bacteria from accessing this essential nutrient [i]. It has very good anti-pseudomonas Continue reading Fighting P. aeruginosa (Part II)
It has never been easy to cure Pseudomonas aeruginosa infections. Few antibiotics nowadays have reliable activity against this problem pathogen that seems to have more built-in resistance features than most other Gram-negatives. In the past, cephalosporins, aztreonam, penems, ciprofloxacin, and aminoglycosides were useful drugs with reliably cidal activity, especially when Continue reading Fighting P. aeruginosa (Part I)