Ensitrelvir for Covid Prevention: This Emperor Has No Clothes

Just imagine you were tasked to conduct a seasonal flu study in household contacts of a symptomatic index case.  Your intervention may be (your choice): pre-season vaccination, pre-exposure prophylaxis, or some non-anti-infective protective measure such as wearing a face mask, taking a vitamin or analgesic that is believed to confer Continue reading Ensitrelvir for Covid Prevention: This Emperor Has No Clothes

Treating Serious CRAB Infections

There are MDR pathogens, and there is carbapenem-resistant A. baumannii, aka CRAB. This surely must be one of the most formidable bacterial organisms. It has resistance mechanisms second to none.  When found in patients, it is very difficult to eradicate and extremely difficult to get rid off, once established in Continue reading Treating Serious CRAB Infections

OLOROFIM in a TIGHT SPOT

Regulatory and development status of Olorofim, a novel antifungal. Continue reading OLOROFIM in a TIGHT SPOT