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CDC Report on Pan-Resistant NDM Klebsiella in Nevada– A Sad Tale

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During the past few weeks the case of a patient with MDR Klebsiella infection has made the news. We are told that this particular pathogen is “resistant to 26 antibiotics”. We were informed that the patient had multiple prior hospitalizations in India, supposedly the origin of the uncontrolled untreatable infection. Continue reading CDC Report on Pan-Resistant NDM Klebsiella in Nevada– A Sad Tale→

Is LAIV Dead or Just on LAIV-Support?

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Very recently we came across several studies in which small differences in design had a major impact on outcomes. A blog is not a good place to dig deeply into the minutiae of study design as the discussion becomes quickly very dry and quite technical. However, readers and clinicians are often unaware how a seemingly small change Continue reading Is LAIV Dead or Just on LAIV-Support?→

The Etiology of CAP Remains Elusive – A Call to Change Antibiotic Prescribing Patterns

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Once upon a time – not so long ago – we were taught the following: Streptococcus pneumoniae was the cause of 90% of CAP cases. That statement was later modified to mean S. pneumoniae was the underlying pathogen in 90% of bacterial cases of CAP, i.e., those with positive cultures from sputum or Continue reading The Etiology of CAP Remains Elusive – A Call to Change Antibiotic Prescribing Patterns→