Tag Archives: dose adjustment

No Easy Day: Dose Calculations for Aminoglycosides and Vancomycin

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Searching data on antibiotic use in surgery prophylaxis, I came across an article from the Mayo Clinic [1].  The authors mention that approx. 75% of patients that developed surgical site infections did not get proper antibiotic prophylaxis.  Errors were made in (1) Continue reading No Easy Day: Dose Calculations for Aminoglycosides and Vancomycin→

Commenting on Comments:  The Ceftaroline Trial Program in CABP

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The ceftaroline (Teflaro®) program was executed at a time when FDA was debating a new CABP Guidance with new outcome measures: no longer was the time-honored TOC assessment acceptable, instead improvement on Day 3-5 was to become the new primary Continue reading Commenting on Comments:  The Ceftaroline Trial Program in CABP→