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Ibuprofen for uUTI (Part 2): Antibiotic or NSAID? Or Both? Or Neither?

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While the news is abuzz with reports of Zika virus coming to a place near you, an interesting article on a much more mundane topic – the treatment of uncomplicated UTIs – should be competing for your attention. It is a publication we have been waiting for, as mentioned in an earlier blog. Results Continue reading Ibuprofen for uUTI (Part 2): Antibiotic or NSAID? Or Both? Or Neither?→

New Treatment Guidelines for Candidiasis – A Major Document to Study

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In a much-quoted analysis, Lee found that most IDSA Guidelines were supported only by Level III quality data, the lowest category of evidence-based support[1]. The article concludes that more well-designed trials were needed, and clinical judgement should ultimately guide patient management. This all sounds fine and good, and the new Continue reading New Treatment Guidelines for Candidiasis – A Major Document to Study→

Aztreonam PLUS Avibactam – A New Bright Star in the Night Sky

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Looking at the molecular structure of ceftazidime (CTAZ) and aztreonam (ATM), the differences are clear, and so are the similarities: ATM does not have the cephem ring structure of CTAZ, only the 4-member beta-lactam ring.  However, the side chains are identical in both CTAZ and ATM which explains the overlapping Continue reading Aztreonam PLUS Avibactam – A New Bright Star in the Night Sky→