Allphase Pharma Consulting, LLC
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The economics of developing antibacterials is a frustrating topic to address. There are unique aspects to the antibiotic market which sets it apart from other medicines, esp. the unique societal aspects of antibiotic use which go beyond the benefit to the individual. IDSA has spoken out in various publications (“Bad Continue reading It’s Not a Free-Enterprise Market, Stupid!
It has grown with each edition, in page numbers, in weight, in numbers of contributors, diseases and pathogens described, and in complexity, with online access and search capabilities. More than most other therapeutic areas, the science of ID has grown in the past decades, thanks to advances in genetics, diagnostics Continue reading Fantastic – The 8th Edition of Mandell’s is Here!
The cartilage damage caused by fluoroquinolones in juvenile beagle dogs is not subtle: blister formation and erosions occur in a dose-dependent fashion resulting in reversible cartilage damage. These lesions can be seen not just histologically but even macroscopically. The animals are unable to walk as weight-bearing joints are predominantly affected. Continue reading The Futile Quest of Proofing a Negative in the Presence of Overwhelming Absence of Harm