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Several reasons have been proposed as explanations why so many S. aureus vaccines have failed in clinical trials. Clearly, the organism has a battery of virulence factors which may require a multipronged approach and neutralizing just a single mechanism with a specific mAb may not suffice.
A recent publication [1] from the team which brought us the Meningococcal B vaccine is of interest from the perspective of vaccine development strategy and feasibility.
This compilation is from many sources and necessarily incomplete as we still have lots to learn about MERS. Please come back periodically for updated information. Status: 7/8/2014 Some tidbits of unknown significance: A close relative of MERS-CoV is carried by the European hedgehog (Erinaceus europaeus). As many children have hedgehogs Continue reading SARS and MERS – a Comparison of the New Corona Viruses