EMBLAVEO (AZTREONAM+AVIBACTAM) Microbiology Testing for MDR Pathogens

The discussion emphasizes challenges in clinical antibiotic trials which failed to effectively target multi-drug resistant (MDR) pathogens. It advocates for using rapid PCR diagnostics to streamline trials, ensuring focus on pathogens of concern, and calls for regulatory adaptations to enhance study design and antibiotic testing efficacy. Continue reading EMBLAVEO (AZTREONAM+AVIBACTAM) Microbiology Testing for MDR Pathogens

JOURNAL BUSINESS vs EDITORIAL OVERSIGHT

New medical and science journals pop up in our mailbox on a biweekly basis.  Offers to join as Editor, solicitation for articles based on past publications, invitations for subject reviews come as unsolicited emails.  Medical publication houses, old and new, are expanding, adding more and more subspecialties to their established Continue reading JOURNAL BUSINESS vs EDITORIAL OVERSIGHT

To Kill A Mocking Bug – of the CRKP or CRAB Variety

Meropenem stands out as an antibiotic to be used first in ESBL and MDR infections, given its efficacy profile and safety record (see earlier blog). It also would seem to be appropriate to use relatively high doses or prolonged infusion times – or both – to improve T>MIC for the Continue reading To Kill A Mocking Bug – of the CRKP or CRAB Variety