Some Curious Tidbits

Were you aware that… there is also an amphotericin A which has antifungal properties?  It has a broader spectrum but is much less potent than Amphotericin B and therefore not being used. [1] in 1946, the first truly randomized and partially blinded study was started in Britain under the leadership of the Continue reading Some Curious Tidbits

Some Thoughts about Eravacycline Based on the Phase 2 cIAI Study

Solomkin et al. conclude that the efficacy and safety of eravacycline compares favorably to the control drug, ertapenem.[1]  This top-level assessment is made with the usual caveats (insufficient statistical power, small sample size), but a few points deserve comment. Eravacycline is a fluorocycline; as a tetracycline derivative it follows into Continue reading Some Thoughts about Eravacycline Based on the Phase 2 cIAI Study

Aeromonas salmonicida: Trouble for Aquaculture with Drug Resistance

Aeromonas salmonicida causes furunculosis in salmon hatcheries and in freshwater fish.  The organism has several recognized virulence mechanisms including the T3SS [1].