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Tag Archives: Vera Therapeutics

BAFF / APRIL Inhibitors Homing in on IgAN

Posted on May 30, 2025 by Harald — No Comments ↓

Today we discuss the group of BAFF/APRIL inhibitors, specifically the three TACI mAb constructs that are currently in development. They were tested in a broad gamut of B-cell indications but failed to show efficacy in many. So far, consistent clinical success has been seen only in IgA nephropathy (IgAN), with Continue reading BAFF / APRIL Inhibitors Homing in on IgAN→

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Posted in Recent Literature, The News, The Viewpoint | Tagged AIHA, Allphase Pharma Consulting, Alpine Immune Science, ANCA vasculitis, anifrolumab, APRIL, atacicept, B-cell disorders, BAFF, belumimab, Benlysta, budesonide, CD19, CD20, CD38, eGFR, FABHALTA, FDA, Filspari, gMG, Harald Reinhart, IgA nephropathy, IgAN, iptacopan, ITP, LN, lupus nephritis, membranous nephropathy, MS, multiple sclerosis, myasthenia gravis, Nefecon, povetacicept, proteinuria, RA, Remegen Biosciences, Rituxan, rituximab, Saphnelo, SLE, sparsentan, TACI, telitacicept, UPCR, Vera Therapeutics, Vertex Therapeutics | Leave a reply

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