Where are the Chloramphenicol Derivatives?

The 1st edition of Mandell’s textbook ‘Principles and Practice of Infectious Disease’ was published in 1979.  It has grown ever since in size and numbers of chapters.  Now in its 10th edition, it is and remains an impressive publication, a 2-volume set, a comprehensive reference textbook, kept up-to-date with periodic Continue reading Where are the Chloramphenicol Derivatives?

ANTIBIOTIC USE IN VETERINARY MEDICINE

A ton is a tonne, by any other name.  A tonne, also called a metric tonne, is the equivalent of 1,000 kg.  There are also imperial tonnes and long tonnes which have a slightly different conversion factor:  1 tonne of either is equivalent to 1.01604691 metric tonnes. The amount of Continue reading ANTIBIOTIC USE IN VETERINARY MEDICINE

The CDC and Spectinomycin

Pfizer discontinued US distribution of spectinomycin (Trobicin®) in November 2005; remaining inventory expired in May 2006 [1]. Nonetheless, at the FDA website we still find a Package Insert for Trobicin updated as late as Aug 2012, a thin 6-page leaflet which seems to have survived from the 80s. The drug is Continue reading The CDC and Spectinomycin