Is LAIV Dead or Just on LAIV-Support?

Very recently we came across several studies in which small differences in design had a major impact on outcomes. A blog is not a good place to dig deeply into the minutiae of study design as the discussion becomes quickly very dry and quite technical. However, readers and clinicians are often unaware how a seemingly small change Continue reading Is LAIV Dead or Just on LAIV-Support?

Progress Report: New Antibacterials In the Fight against MDR Bacteria

Since the beginning of this millennium we have seen antibiotic R&D dwindle year after year. There are many reasons for this; while economics are often cited for this decline, the FDA and the ‘Guideline Wars’, i.e., those never ending discussions about regulatory requirements, have contributed to this trend in a Continue reading Progress Report: New Antibacterials In the Fight against MDR Bacteria

Lung Ultrasound has Come a Long Way

The old-fashioned portable chest X-ray is still the preferred way of documenting pneumonia at the bedside. Although more cumbersome, CT scans are also frequently employed for more definitive diagnosis, esp. in the ER or the ICU setting. Historically, ultrasound of the lungs (LUS) was always problematic as the sound waves do Continue reading Lung Ultrasound has Come a Long Way