The Antifungal Landscape – 2

As many in the field have said before, what we really need are antifungals with a truly novel MoA, not minor changes to well-established classes.[1]  There is a shortage of new antifungals for invasive disease. Small improvements in PK will hardly move the field forward or excite investors to engage. Our current Continue reading The Antifungal Landscape – 2

Nikkomycins Are Finally Getting Some Respect

Besides azoles, candins and the polyene class of antifungals there is not much to select from when it comes to systemic fungal infections.  Until the recent arrival of voriconazole and posaconazole, infections caused by molds always required amphotericin B to control.  Only for Candida several good treatments exist on the Continue reading Nikkomycins Are Finally Getting Some Respect