Tag Archives: agammaglobulinemia

Prof Brambell’s FcRn – The Story So Far

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Francis William Rogers Brambell was an Irish scientist who rose to prominence in the middle of the last century.  He is remembered for 2 major accomplishments.  First and foremost, his discovery that passive immunity is transferred from mother to baby.  Based on research in various animal species on the transfer Continue reading Prof Brambell’s FcRn – The Story So Far→

Learning from Set-Backs: The Frustrating Search for a Staphylococcal Vaccine

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Several reasons have been proposed as explanations why so many S. aureus vaccines have failed in clinical trials.  Clearly, the organism has a battery of virulence factors which may require a multipronged approach and neutralizing just a single mechanism with a specific mAb may not suffice.