Should Efavirenz Remain a Tier 1 ART Drug?

In a recent publication Raffi et al. suggest that it may be time to drop efavirenz (Sustiva®) from 1st line HIV treatment recommendations [1].  The authors make the claim that efavirenz was inferior to rilpivirin (Edurant®) and dolutegravir (Tivicay®) in a total of Continue reading Should Efavirenz Remain a Tier 1 ART Drug?

HIV Therapy Guidance Recommendations Diverge, Show US Bias

US doctors seem to be very willing to start drugs earlier in disease, while their EU colleagues are slower and more conservative.  Recent examples: the ever-wider indication for statins, the disproportionate uptake of drugs for attention-deficit / hyperactivity and opioids Continue reading HIV Therapy Guidance Recommendations Diverge, Show US Bias