Ebola – Fact Sheet (Updated 10/3/2014)

The WHO just released the latest statistics on what has turned into the largest ever outbreak of Ebola virus (EBOV) in Africa.  The epidemic started in Guinea around December 2013. As of 7/27/2014, Guinea, Liberia, Nigeria, and Sierra Leone have reported a total of 1323 cases, with 729 fatalities [i].  Most Continue reading Ebola – Fact Sheet (Updated 10/3/2014)

What is the “Niche” for Ceftolozane / Tazobactam?

There are currently a total of 6 beta-lactam + beta-lactamase inhibitor combinations in clinical trials. It will be a steep learning curve for the pharma reps (and physicians) to understand the resistance classifications, the confusing ESBL definitions, the CRE nomenclature, and how this all matters in clinical practice, on the Continue reading What is the “Niche” for Ceftolozane / Tazobactam?

Greenwood: Antimicrobial Drugs – Chronicle of a Twentieth Century Medical Triumph

This is not meant to be a book review.  I just want to express my gratitude to Prof. Greenwood for writing a book about the remarkable story of antibiotic discovery and development of the last century.  It is clearly a labor of love, written with knowledge, enthusiasm, wisdom and perspective.