The 10 x ’20 Initiative – A Retrospective

It started all so well with fanfare and great expectations. Fifteen years ago, the 10 x ’20 initiative got underway. Its goals were spelled out clearly: To ‘Pursue a Global Commitment to Develop 10 New Antibacterial Drugs by 2020 ’[3].  It was driven by ID clinicians and by antibiotic developers concerned Continue reading The 10 x ’20 Initiative – A Retrospective

THE UTILITY OF FUTILITY

Companies can stop studies before reaching projected enrollment numbers.  It could be a decision based on a planned interim analysis (IA) or it could be for  ‘administrative’ reasons.  The latter may not indicate that a company has fallen on hard times financially; it could be the result of operational problems Continue reading THE UTILITY OF FUTILITY

Connections: From Mima/Herellea to Acinetobacter to the Double Helix to Lwoff to … CRAB

There once was a Scientific American section authored by science historian James Burke called ‘Connections”. In it James Burke, a true renaissance man, showed us how an ‘internet’ of serendipitous encounters, connections between persons, places and events led to advances in science. His delightful tours through history are testimony to Continue reading Connections: From Mima/Herellea to Acinetobacter to the Double Helix to Lwoff to … CRAB