Allphase Pharma Consulting, LLC
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PLEASE SHARE YOUR OPINION AND VOTE BELOW It has always been a bit of a gamble: Predicting the main circulating flu types and subtypes for the next season based on information from the previous season is an educated guess. It works well most of the time but fails when there is Continue reading Vaccine Mismatch – The Influenza Season 2014 / 2015
..when it comes to FDA review of antibiotic NDAs. Some seem to have forgotten the dismal record of antibiotic approvals in the last 15 years, and the long list of failed submissions. Many failed not because of lack of efficacy or a bad safety profile but because of changes in Continue reading No Such Thing as a Free Ride…
It is amazing how modifications to the azole structure have produced ever more potent, ever more useful antifungals. Ketoconazole had limited usability because of its many side effects related to off-target sterol synthesis inhibition, solubility (or lack thereof) and erratic absorption. Solublity was also an issue for itraconazole and posaconazole. Continue reading Cresemba / Isavuconazole: Not Just Another Azole