ANTIBIOTIC DEVELOPMENT IN PHARMA IS DEAD – FOR NOW

This is a somewhat nostalgic retro blog.  I was leafing through a book by Vince Andriole called ‘The Quinolones’.[1]  First released in 1988, its third edition is from 2000.  It provided in-depth coverage of quinolone chemistry, PK, microbiology, efficacy and safety.  It was a great review of the large and Continue reading ANTIBIOTIC DEVELOPMENT IN PHARMA IS DEAD – FOR NOW

Treating GC in the Face of Dwindling Antibiotic Options – (1)

Looking across the Northern border it is clear that CDC Guidelines are not universally followed even in North America. Public Health Canada still recommends cefixime for uncomplicated gonorrhea (GC), albeit at the high single oral dose of 800 mg [1]. In the US, CDC has opted for combination treatment with ceftriaxone Continue reading Treating GC in the Face of Dwindling Antibiotic Options – (1)