Allphase Pharma Consulting, LLC
A Professional Service Provider for the Pharma Industry
Francis William Rogers Brambell was an Irish scientist who rose to prominence in the middle of the last century. He is remembered for 2 major accomplishments. First and foremost, his discovery that passive immunity is transferred from mother to baby. Based on research in various animal species on the transfer Continue reading Prof Brambell’s FcRn – The Story So Far
Today we discuss the group of BAFF/APRIL inhibitors, specifically the three TACI mAb constructs that are currently in development. They were tested in a broad gamut of B-cell indications but failed to show efficacy in many. So far, consistent clinical success has been seen only in IgA nephropathy (IgAN), with Continue reading BAFF / APRIL Inhibitors Homing in on IgAN