Aerosolized Antibiotics & Selling Nebulizers

“The medicine comes for free, just pay us for the inhaler” should be the marketing slogan for this group of therapeutics.  Nebulizers are good business: hard to copy as a delivery system, they are a great opportunity to ‘evergreen’ off-patent antibiotics. The inhalational route to administer antibiotics is clearly attractive.  Continue reading Aerosolized Antibiotics & Selling Nebulizers

A GO / NO GO decision:  Delafloxacin Stumbles in Gonorrhea Study

The treatment history of N. gonorrhoeae makes for fascinating reading.  This organism has always been able to keep the upper hand in the war of bug versus drug.  Once susceptible to sulfa drugs, to penicillin, tetracyclines and fluoroquinolones, it sequentially become resistant in the matter of a decade to every Continue reading A GO / NO GO decision:  Delafloxacin Stumbles in Gonorrhea Study

Greenwood: Antimicrobial Drugs – Chronicle of a Twentieth Century Medical Triumph

This is not meant to be a book review.  I just want to express my gratitude to Prof. Greenwood for writing a book about the remarkable story of antibiotic discovery and development of the last century.  It is clearly a labor of love, written with knowledge, enthusiasm, wisdom and perspective.