HANTA & WHAT’S NEXT

By now, we’ve had a chance to brush up on the Hanta virus, esp. the Andes variety which caused a mini-epidemic on the arctic cruise ship MV Hondius.  Named after Hantaan, the river in South Korea where the disease first emerged, we give credit to Dr. Ho Wang Lee, the Continue reading HANTA & WHAT’S NEXT

Ensitrelvir for Covid Prevention: This Emperor Has No Clothes

Just imagine you were tasked to conduct a seasonal flu study in household contacts of a symptomatic index case.  Your intervention may be (your choice): pre-season vaccination, pre-exposure prophylaxis, or some non-anti-infective protective measure such as wearing a face mask, taking a vitamin or analgesic that is believed to confer Continue reading Ensitrelvir for Covid Prevention: This Emperor Has No Clothes

OFF-TARGET ANTIBODIES

Quick: What do you associate with the abbreviation ‘TCR’?  Does your immunology-trained mind automatically default to ‘T-cell receptor’?  Or is your first guess ‘Tissue Cross Reactivity?  Our neural networks can deal with ambivalence and will make the right associations, eventually.  Language is imprecise by design and allows for wobble. Things Continue reading OFF-TARGET ANTIBODIES