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You may be aware of recent food product recalls associated with food poisoning due to listeria contamination: ready-to-eat products, deli meats, sandwiches, protein snacks, chicken, turkey, cheese and dairy products. The list is long as Listeria is ubiquitous in the environment. One can find it in meat and milk/cheese products Continue reading LISTERIA: Food Recalls, Outbreaks, and Resistance
Development pf antibacterials differs in several important ways from drug development in other areas, and the lack of standard dose-finding is just one of them. Dose-finding in its most basic form involves ascending amounts of drug for efficacy and safety; for antibiotics, however, an effective dose can be predicted nowadays Continue reading Efficacy and Treatment Duration: Where is the Tipping Point?
When searching for FtsZ inhibitors on PubMed, there are 187 hits. When narrowing down the search looking for clinical trials only, there are none. Taxis Pharmaceuticals obtained QIDP status for its candidate drug TXA-709 in late 2016 and it is still in preclinical testing. The drug’s target, bacterial replication machinery Continue reading TXA-709 – New Kid on the Block