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A Critical Review of WHO’s List of Antibacterials in Clinical Development

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WHO compiles a list of antibacterials in clinical development on a regular basis, the last in mid-2024 [1].  The information is up-to-date and detailed: it provides MoA and antibacterial spectrum, coverage of problem pathogens, the development phase, and whether it can be considered an ‘innovative’ drug (based on a set Continue reading A Critical Review of WHO’s List of Antibacterials in Clinical Development→

Some Thoughts about the New Coronavirus Syndrome and its Transmission

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First and upfront, let’s call this virus WARS*, which stands for Wuhan Associated Respiratory Syndrome.  President Xi Jingping called for a war against the new virus, and a war it is.  Therefore our acronym makes intuitive sense.  The naming of new viruses is getting politized and silly: yes, we need Continue reading Some Thoughts about the New Coronavirus Syndrome and its Transmission→

Connections: From Mima/Herellea to Acinetobacter to the Double Helix to Lwoff to … CRAB

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There once was a Scientific American section authored by science historian James Burke called ‘Connections”. In it James Burke, a true renaissance man, showed us how an ‘internet’ of serendipitous encounters, connections between persons, places and events led to advances in science. His delightful tours through history are testimony to Continue reading Connections: From Mima/Herellea to Acinetobacter to the Double Helix to Lwoff to … CRAB→