Tag Archives: LPS

A Critical Review of WHO’s List of Antibacterials in Clinical Development

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WHO compiles a list of antibacterials in clinical development on a regular basis, the last in mid-2024 [1].  The information is up-to-date and detailed: it provides MoA and antibacterial spectrum, coverage of problem pathogens, the development phase, and whether it Continue reading A Critical Review of WHO’s List of Antibacterials in Clinical Development→

Two New Approaches For Dealing with Sepsis / Toxemia

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There is hardly an indication which has accumulated more failed clinical trials than the sepsis area.  Called first bacteremia, later sepsis, sepsis syndrome or septic shock, there have been numerous attempts to influence the cascade of events that eventually lead Continue reading Two New Approaches For Dealing with Sepsis / Toxemia→