ANTIBIOTIC USE IN VETERINARY MEDICINE

A ton is a tonne, by any other name.  A tonne, also called a metric tonne, is the equivalent of 1,000 kg.  There are also imperial tonnes and long tonnes which have a slightly different conversion factor:  1 tonne of either is equivalent to 1.01604691 metric tonnes. The amount of Continue reading ANTIBIOTIC USE IN VETERINARY MEDICINE

A Critical Review of WHO’s List of Antibacterials in Clinical Development

WHO compiles a list of antibacterials in clinical development on a regular basis, the last in mid-2024 [1].  The information is up-to-date and detailed: it provides MoA and antibacterial spectrum, coverage of problem pathogens, the development phase, and whether it can be considered an ‘innovative’ drug (based on a set Continue reading A Critical Review of WHO’s List of Antibacterials in Clinical Development

TXA-709 –  New Kid on the Block

When searching for FtsZ inhibitors on PubMed, there are 187 hits. When narrowing down the search looking for clinical trials only, there are none. Taxis Pharmaceuticals obtained QIDP status for its candidate drug TXA-709 in late 2016 and it is still in preclinical testing. The drug’s target, bacterial replication machinery Continue reading TXA-709 –  New Kid on the Block